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lipL [2019-05-09 11:52:57]

Octanoyl-[protein|58CF62EBA28E77668A0B5319142C8AC20D81CD8A|GcvH]:protein N-octanoyltransferase

locus

BSU37640

5.27

31.27 kDa

protein length

281 aa Sequence Blast

gene length

846 bp Sequence Blast

function

lipoic acid metabolism

product

Octanoyl-[protein|58CF62EBA28E77668A0B5319142C8AC20D81CD8A|GcvH]:protein N-octanoyltransferase

essential

2.3.1.204

synonyms

ipa-90d,ywfL

Outlinks

KEGG BsubCyc SubtiList UniProt Expression Browser

Genomic Context

Hide small RNAs Zoom:

categories

[category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.7|Biosynthesis and scavenging of lipoic acid]

Gene

Coordinates

3,863,415 → 3,864,260

The protein

Protein family

Octanoyltransferase LipL family (single member, according to UniProt)

Structure

[PDB|2P5I] (from ''Bacillus halodurans'', 56% identity)

Expression and Regulation

Operons

genes

[gene|F2E881F4BE0968C75BD75A5EFF4C7CA642034796|lipL]

description

[Pubmed|9353933]

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Biological materials

Mutant

MGNA-B667 (ywfL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1666 NBRP B. subtilis, Japan]

BKE37640 (Δ[gene|F2E881F4BE0968C75BD75A5EFF4C7CA642034796|lipL]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE37640 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTATGTAAAACCCTTTC, downstream forward: _UP4_TGAACGTTCTTCGCATGCCG

BKK37640 (Δ[gene|F2E881F4BE0968C75BD75A5EFF4C7CA642034796|lipL]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK37640 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTATGTAAAACCCTTTC, downstream forward: _UP4_TGAACGTTCTTCGCATGCCG

References

Reviews

27074917

Original publications

9353933,21338420,21338421